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SSA could not be possible without the generous support of Drs. Herbert A. and Betty Lou Lubs and the Science, Society, and the Arts Research Conference Endowment. We are deeply grateful!
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Friday, March 17 • 3:00pm - 4:15pm
Easel 79: Ribosome Processivity

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Protein synthesis is a vital process for organisms to maintain life. To produce proteins, mRNA, a temporary copy of genetic material, is transported into the cytoplasm and is translated by ribosomes. During translation, ribosomes attach onto an mRNA to translate it into functional protein. Ribosome processivity is the likelihood that a ribosome will finish translation once it has attached. Ribosome processivity is not well-studied,but we do know that ribosomes must be highly processive especially when they are required to translate large proteins.
However, we do not know what factors aid ribosome processivity or even what mRNA sequences cause ribosomes to abort translation. By investigating ribosome processivity in vivo, we will be able to further study the factors that affect ribosome processivity. Here, we characterize a reporter mRNA that allows us to investigate ribosome processivity in vivo. We observe that not all cells in a population contain processive ribosomes.

Friday March 17, 2017 3:00pm - 4:15pm
Leyburn Library