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SSA could not be possible without the generous support of Drs. Herbert A. and Betty Lou Lubs and the Science, Society, and the Arts Research Conference Endowment. We are deeply grateful!
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Friday, March 17 • 3:00pm - 4:15pm
Easel 10: Elucidating the anti-quorum sensing compounds in aqueous Rose leaf extracts with Serratia marcescens

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Serratia marcescens is a motile, pigmented member of the family Enterobacteriaceae that uses a density-determining process called quorum sensing to regulate motility and pigment production. Aqueous leaf extracts of the Rose bush have been demonstrated to inhibit quorum sensing in a dose-dependent manner in this bacterium. Two quorum sensing regulated phenotypes, swarming, a form of socially coordinated movement, and prodigiosin production, the synthesis of a characteristic red pigment, were used as quorum sensing indicators. Quorum sensing inhibiting agents are of interest both therapeutically and scientifically, as quorum sensing pathways continue to be characterized. The current project focuses on identifying the active compounds in the aqueous Rose extract using thin layer chromatography and mass spectrometry.


Friday March 17, 2017 3:00pm - 4:15pm
Leyburn Library